Functional Organotypic Cultures of Prostate Tissues

Functional Cftr in Crypt Epithelium of Organotypic Enteroid Cultures

2 3 4 Functional Cftr in Crypt Epithelium of Organotypic Enteroid Cultures 5 from Murine Small Intestine 6 7 8 By 9 10 Jinghua Liu, Nancy M. Walker, Matthew T. Cook, Akifumi Ootani and Lane L. 11 Clarke 12 13 Dalton Cardiovascular Research Center, University of Missouri, Columbia, MO 65211 14 Department of Biomedical Sciences, University of Missouri, Columbia, MO 65211 15 Akimoto Hospital, Fuku...

Organotypic cultures as tools for functional screening in the CNS.

A major challenge for the pharmaceutical industry is the development of relevant model systems in which knowledge gained from high-throughput, genomic and proteomic approaches can be integrated to study function. Animal models are still the main choice for such studies but over the past few years powerful new in vitro systems have begun to emerge as useful tools to study function. Organotypic c...

Organotypic hippocampal slice cultures.

The hippocampus, a component of the limbic system, plays important roles in long-term memory and spatial navigation. Hippocampal neurons can modify the strength of their connections after brief periods of strong activation. This phenomenon, known as long-term potentiation (LTP) can last for hours or days and has become the best candidate mechanism for learning and memory. In addition, the well ...

Organotypic Cultures of the Rat Retina

Organotypic vibrosections: Novel whole sagittal brain cultures

In vitro cell culture models are of enormous importance in neuroscience research and organotypic brain slices are found to be a potent model very close to the in vivo situation. Brain slices can be cultured as single slices or as co-slices. However, there is need to culture whole brain sections, containing the complex functional architecture. The aim of the present study was to develop and char...